This research is especially useful for cancer patients because chemotherapy drugs, such as cisplatin, cause nausea and vomiting.
Carboplatin costs £205.71 against £17.90 for cisplatin, but the total treatment costs are reduced from £347.90 to £228.77.
In the case of antineoplastic agents such as paclitaxel, cisplatin and thalidomide, the neuropathy is dose-dependent and doselimiting; patients often cannot tolerate the doses necessary to treat the underlying cancer.
The results of our study show that cisplatin has no effect on either minisatellite mutations or crossover frequencies during the most important stages of mouse spermatogenesis.
Epidermal growth factor receptor pathway analysis identifies amphiregulin as a key factor for cisplatin resistance of human breast cancer cells.
Unfortunately, carboplatin shows a marked degree of cross-resistance when compared to cisplatin.
Acute emesis usually begins 2 to 4 hours after cisplatin administration and peaks at 6 hours (23;26).
T he drugs best known t o cause anosmia are cisplatin and neuroleptic drugs.