gene amplification Meaning & Definition

  • En [ ˈdʒiːn ˌæm.plɪ.fɪˈkeɪ.ʃən]
  • Us [ ˈdʒiːn ˌæm.plɪ.fɪˈkeɪ.ʃən]

Meaning of gene amplification In English

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Examples of gene amplification

  • Gene amplification occurs in both oogenesis and spermatogenesis, the difference consisting in the ribosomal gene amplification mechanism.

  • Chronic treatment with physiological concentrations of ethanol (0.36%, 1.36%) induces micronuclei, nucleoplasmic bridges, and nuclear buds, which are indicative of chromosome loss and breakage, chromosome rearrangement and gene amplification, respectively.

  • Somatic recombination, gene amplification and cancer.

  • Overexpression can happen in one of three ways: as a result of gene amplification, impaired protein degradation, or chromosomal translocation.

  • Some scientists suggest that this result may have been caused by selection for gene amplification and/or a higher mutation rate in cells unable to divide.

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