Examples of endoplasmic reticula

• Most morphological alterations were presented by the vacuolization of embryonic cells, disintegrated cytoplasm, swollen mitochondria and dilatation in rough endoplasmic reticula.

• Mutant cells suffer disruptions in their endoplasmic reticula, leading to disease.

• Thapsigargin raises cytosolic (intracellular) calcium concentration by blocking the ability of the cell to pump calcium into the sarcoplasmic and endoplasmic reticula which causes these stores to become depleted.