In the sphere of music, electronic instruments and computers developed in ways that profoundly affected performance and composition practices.
Contaminated water not only affects humans but can profoundly alter ecosystems, suggesting again a complex and wide-ranging web of reverberations.
The developing physiology of newborns and infants can be profoundly affected by cardiopulmonary bypass.
Exacerbating this position, many of the drama's protagonists understand themselves as profoundly isolated by their exceptional situations (whether ennobled or degraded) and attendant emotions.
All this is profoundly confused, with confusion occurring on at least two distinct levels.
The island's rapid integration into the national and world economy and a vibrant indigenous movement have profoundly influenced the everyday lives of island residents.
All participants in this group were severely or profoundly deaf and their parents, who were deaf, signed to them from infancy.
However, such developmental impulses are profoundly compromised by the diverse and often contradictory manner by which the projects are being implemented on the ground.
