You put the mechanical surgeon inside the blood vessel, and it goes into the heart and 'looks' around.
Once a constricted blood vessel falls below a critical size, it supplies no oxygen to the system.
Increased vascular supply to the tumour via the induction of new blood vessel formation (angiogenesis) encourages tumour growth and facilitates metastasis to distant sites.
This creates space away from the blood vessel.
These, in turn, cause the blood vessel to open or close, and drive the movement of the live and dead cells.
During re-endothelialisation of wounds to the blood vessel wall, endothelial cells extend protrusive contacts in order to close gaps in the cell layer.
After the cells away from the blood vessel have died, they are degraded.
There is an imbalance of signals from the corresponding retinae because one is shadowed by the blood vessel and the other receives normal stimulation.
