The reason is that as with sickle-cell anaemia the condition confers some resistance to malaria.
No-one can save those who suffer from sickle cell anaemia.
Is it really true that sickle-cell anaemia (p. 7) is lethal earlier than thallassaemia (sic)?
The bestknown example is probably that of the sickle cell gene.
This figure illustrates the complexity of the pathophysiology of sickle cell anemia.
Hemoglobinopathies such as the sickle cell disorders and thalassemias tend to affect mainly people from certain ethnic minority groups.
The receptor critical for sickle cell adhesion to laminin.
However, careful studies are warranted in sickle cell patients given the side effect profile of sulfasalzine, which includes serious gastrointestinal bleeding and nephrotoxicity.
