This suggests that most irregular cells are likely to arrest at prophase/prometaphase, whereas those with less severe defects may be able to proceed to anaphase.
During assembly of follicles the oocytes increase in size and enter the meiotic prophase when the number of nucleoli in the nucleus increases.
This maturation is later blocked during the early stages of prophase.
Pairing behaviour during male meiotic prophase indicates that these autosomes are homologues.
Around 11-12 weeks of gestation, the germ cells situated innermost in the cortex, enter prophase of the first meiotic division.
In the mouse, as in most vertebrates, ovarian oocytes arrest at the diplotene stage of the first meiotic prophase until puberty.
The pregranulosa cells migrate through the connective tissue fibrils of the stroma and arrive at the vicinity of the meiotic prophase oocytes.
It looks as though there is an intact nucleus and the cells are considered to be in prophase of early embryonic divisions.
