Pathology is similar as in rats, with apoptosis and hepatocellular hyperplasia.
Those who develop cirrhosis have a 20-fold greater risk of hepatocellular carcinoma.
These studies elucidated its virology, immunology, transmission and clinical manifestations, including its causal link to chronic hepatitis, cirrhosis and hepatocellular carcinoma.
No dysuria or hepatocellular toxicity was reported.
Approximately 20-30 percent of people initially infected develop cirrhosis within 20 years (16), and 1-4 percent of these people are at high risk of hepatocellular carcinoma (6).
Such procedures range from radiofrequency ablation of hepatocellular carcinoma to laser lumbar discectomy; and from vagal nerve stimulation for epilepsy to uterine artery embolization of fibroids.
What accounts for the lower rate is the presence of other health conditions, like hepatocellular carcinoma, that need not accompany the chronic condition.
Significantly increased estimated relative risks of 6.5 and 6.0 were seen with cholangiocarcinoma, but no significant association was seen with the occurrence of hepatocellular carcinoma.
