0 a type of small tumour that grows slowly and is most commonly found in the stomach or intestines. It can be benign (= harmless) or malignant (= likely to cause death if untreated) --
Carcinoid tumors may cause increased excretion of tryptophan, 5-hydroxytryptophan and histamine as well as serotonin.
When neuroendocrine cell hyperplasia and tumorlets are extensive, they represent the rare preinvasive lesion for carcinoids known as diffuse idiopathic pulmonary neuroendocrine cell hyperplasia.
Entero-pancreatic gastrinomas and thymic and bronchial carcinoids are the leading cause of morbidity and mortality.
Typical carcinoids have cells with stippled chromatin and a moderate quantity of cytoplasm.
Alternatively, the flushing and diarrhea observed in carcinoid syndrome is caused by elevated levels of circulating serotonin.
Carcinoid heart disease was identified in 1952 and carcinoid fibrosis in 1961.
In malignant carcinoid tumors with carcinoid syndrome, the median survival has improved from two years to more than eight years.
The most common originating sites of carcinoid is the small bowel, particularly the ileum; carcinoid tumors are the most common malignancy of the appendix.
