0 the fact of some areas of skin being darker than others, often caused by skin damage or certain medical conditions :
Hyperpigmentation may develop in the affected skin as the lesions persist.
The cucumber diminishes hyperpigmentation, and reduces fine lines and wrinkles.
Melasma is an acquired hyperpigmentation that occurs in sun-exposed areas.
The neuropathy occurs in combination with systemic features, including hepatomegaly, splenomegaly, hyperpigmentation, gynaecomastia and/or testicular atrophy and sclerotic bone lesions.
Hyperpigmentation is excess coloration, or darkening of the skin, while hypopigmentation is a diminished or palid coloring to the skin.
Estheticians treat a wide variety of skin issues that are cosmetic in nature, such as mild acne, hyperpigmentation, and aging skin.
Other clinical features may include palmoplantar hyperkeratosis, nail dystrophy, intellectual deficit, disturbances of skin pigmentation (perioral and periorbital hyperpigmentation, vitiligo, and perinevic leukoderma) and hypodontia.
Deposition in the pancreas leads to diabetes and in the skin leads to hyperpigmentation.