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Evaluation of alignments is usually carried out with respect to some previously created gold standard alignments.
Another concern with the design of this study is reference test bias, inherent with the use of an "imperfect" gold standard.
However, as all constituent diagnostic methods have imperfect sensitivity, this ' gold standard ' cannot have perfect sensitivity either.
If a gold standard is available, even for a subset of indications, assess association of the panel findings with the gold standard.
All subjects were blinded to both the previously contoured "gold standard" anatomy outlines and each other's outlining.
Because of their strong internal validity, traditional blinded trials are still the gold standard for efficacy assessment of medical interventions.
Life-span changes, interindividual differences, and intra-individual variability in brain-behavior mappings are not adequately described or explained in relation to a "gold standard" of normality.
The gold standard provided just such an ideology, supported by a rhetoric of morality and rectitude.
The mentality of the gold standard proved resistant to change even under the most pressing economic circumstances.
In this environment the gold standard became an engine for de-ation.
Or, more likely, not thinking through the reformulation and implications of this "gold standard" consent process.
A second disadvantage is that controlled experiments, often taken to be the gold standard of causal inference, are much less available to social scientists.
The current 'gold standard' for diagnosis of bacteraemia is still the blood culture.
This is usually achieved by comparing an instrument against one or more 'gold standard' instruments.
In the absence of a serological 'gold standard', the search for improvements in diagnostic accuracy continues.
