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In this article, we review available studies concerning chlamydial infection and the elicitation of an autoimmune response in the human host.
Anecdotal observations have been made of autoimmune disease remission in patients who have undergone allogeneic bone marrow transplantation as a result of coincidental haematological malignancies.
Genetic analysis of autoimmune type 1 diabetes mellitus in mice.
Some of these have been hypothesized to share common immunopathogenesis, such as primary biliary cirrhosis, primary sclerosing cholangitis and autoimmune forms of hepatitis and cholangitis.
Dysregulated production of these cytokines has been associated with several autoimmune disorders and chronic inflammatory processes.
It is for such reasons that these bacterial gene products have long been considered attractive candidates for engendering an autoimmune response in the infected host.
Maternal characteristics and risk of severe neonatal thrombocytopenia and intracranial hemorrhage in pregnancies complicated by autoimmune thrombocytopenia.
As with many other autoimmune diseases, most patients require long-term treatment, but a small proportion go into remission and can come off treatment.
By the same token, individuals with an extremely sensitive immune system may more easily fall prey to severe allergies or autoimmune diseases.
Pernicious anaemia, as with other autoimmune conditions, is also encountered more commonly in the elderly than in the younger population.
Secondary autoimmune haemolysis should eventually respond to treatment of the underlying cause, or to removal of the offending drug.
It must be emphasised that there would of course be no rejection or autoimmune reactions occurring in the case of autotransplantation.
Clinically significant newly presenting autoimmune thrombocytopenic purpura in adults: a prospective study of a population based cohort of 245 patients.
It is an autoimmune disorder and thus is more common in women of childbearing age.
Moreover, gene polymorphisms that affect function might contribute to the triggering of autoimmune disease by as-yet-unknown mechanisms.