0 a condition in which someone is born with an extra chromosome (= one of the rod-like structures found in all living cells which is part of an animal's or plants genetic material), which results in them having learning difficulties:
This discovery led to a much safer form of screening for Down's syndrome that is now in wide use.
Two of the friends that feature in the film, Sean and Bobby, have Down's Syndrome.
We decided to tell the story from the point of view of someone with Down's Syndrome.
She worries about the future for her Down's syndrome daughter.
